Nayeli is from the Zapotec language of Oaxaca, Mexico — meaning "I love you" or "my love." A top-500 US baby name since 2004, peaking at #277 in 2009. The Zapotec civilization — one of the Indigenous Mesoamerican peoples, whose Monte Albán capital flourished from 500 BCE to 750 CE; about 460,000 modern Zapotec speakers in Mexico maintain the language and naming tradition; Nayeli is among the most-popular contemporary Zapotec-origin given names worldwide. Saint Nayeli is not a canonical saint, but the name is frequently used in modern Mexican Catholic baptisms.
Nayeli does not currently appear in the US Social Security Administration's top 1,000 girls' names, so we don't publish a US rank or birth count for it. That says nothing about the name's standing elsewhere in the world — only that it sits outside the ranked US data we rely on.
In Pythagorean numerology the letters of Nayeli reduce to 3, The Communicator. This is a traditional interpretive system, not a factual claim about the name.