Polyxene is from the Greek Πολυξένη (Poluxénē — much-hosting, hospitable to many) — from Greek polys (many) + xenos (guest/stranger). Polyxene is one of the Greek feminine names — central to traditional Greek epic heritage. Greek feminine name reflecting Greek tragic heritage.
Polyxene does not currently appear in the US Social Security Administration's top 1,000 girls' names, so we don't publish a US rank or birth count for it. That says nothing about the name's standing elsewhere in the world — only that it sits outside the ranked US data we rely on.
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In Pythagorean numerology the letters of Polyxene reduce to 8, The Visionary. This is a traditional interpretive system, not a factual claim about the name.